High-Protein Pizza Breakfast Casserole

Featured in: Weekend Rustic Recipes

This hearty breakfast casserole combines a simple Greek yogurt dough with a fluffy egg layer, turkey pepperoni, and melted mozzarella and cheddar. The yogurt-based crust creates a pizza-like foundation while keeping things light. Each serving delivers 22 grams of protein, making it perfect for fueling busy mornings or meal prep Sundays.

Updated on Mon, 09 Feb 2026 17:57:57 GMT
Freshly baked High-Protein Breakfast Casserole with golden cheese and turkey pepperoni, served warm on a rustic cutting board. Save
Freshly baked High-Protein Breakfast Casserole with golden cheese and turkey pepperoni, served warm on a rustic cutting board. | olivebriar.com

Combine the comfort of a morning breakfast bake with the savory flavors of a classic pizza. This High-Protein Pizza Breakfast Casserole uses a clever Greek yogurt dough base to create a satisfying, protein-forward meal that feels indulgent yet remains healthy. Featuring fluffy eggs, turkey pepperoni, and melty cheese, it is an ideal choice for a nutritious start to your day.

Freshly baked High-Protein Breakfast Casserole with golden cheese and turkey pepperoni, served warm on a rustic cutting board. Pin it
Freshly baked High-Protein Breakfast Casserole with golden cheese and turkey pepperoni, served warm on a rustic cutting board. | olivebriar.com

What's for Dinner Tonight? 🤔

Stop stressing. Get 10 fast recipes that actually work on busy nights.

Free. No spam. Just easy meals.

Whether you are feeding a crowd at brunch or preparing your meals for the week, this casserole delivers on flavor and nutrition. The combination of mozzarella and reduced-fat cheddar provides a perfect melt, while the turkey pepperoni adds that signature savory kick without the extra fat of traditional pepperoni.

Ingredients

Tired of Takeout? 🥡

Get 10 meals you can make faster than delivery arrives. Seriously.

One email. No spam. Unsubscribe anytime.

  • 1 ½ cups (180 g) all-purpose flour
  • 2 teaspoons baking powder
  • ½ teaspoon salt
  • 1 cup (240 g) plain Greek yogurt (nonfat or 2%)
  • 8 large eggs
  • ½ cup (120 ml) low-fat milk
  • 1 cup (100 g) shredded part-skim mozzarella cheese
  • ½ cup (50 g) shredded reduced-fat cheddar cheese
  • ½ cup (60 g) turkey pepperoni slices
  • ½ teaspoon dried oregano
  • ½ teaspoon garlic powder
  • ¼ teaspoon black pepper
  • 2 tablespoons chopped fresh parsley (optional)
Product image
Organize kitchen cleaning supplies and cooking essentials on the wall to keep prep areas tidy and accessible.
Check price on Amazon

Instructions

Step 1
Preheat your oven to 375°F (190°C). Lightly grease a 9x13-inch (23x33 cm) sheet pan or casserole dish.
Step 2
In a medium bowl, whisk together the flour, baking powder, and salt. Add the Greek yogurt and mix with a spoon until a shaggy dough forms. Knead briefly until smooth.
Step 3
Press the dough evenly into the prepared pan, forming a thin base.
Step 4
In a large bowl, whisk together the eggs, milk, oregano, garlic powder, and black pepper until well combined.
Step 5
Pour the egg mixture evenly over the dough base.
Step 6
Sprinkle both cheeses over the eggs. Top with turkey pepperoni slices.
Step 7
Bake for 20–25 minutes, or until the eggs are set and the cheese is golden and bubbly.
Step 8
Let cool for 5 minutes, then garnish with fresh parsley if desired. Slice and serve warm.

Zusatztipps für die Zubereitung

Ensure you lightly grease the pan to prevent the dough from sticking. When making the Greek yogurt dough, knead it just enough to become smooth; over-kneading can lead to a tougher crust texture.

Still Scrolling? You'll Love This 👇

Our best 20-minute dinners in one free pack — tried and tested by thousands.

Trusted by 10,000+ home cooks.

Varianten und Anpassungen

For extra nutrition, consider adding diced bell peppers, mushrooms, or fresh spinach into the egg mixture. You can also substitute the turkey pepperoni with chicken sausage or vegetarian pepperoni to suit your dietary preferences.

Serviervorschläge

Garnish the finished dish with fresh parsley for a burst of color. For a true pizza experience, serve each slice with a side of warm marinara sauce for dipping.

A hearty slice of High-Protein Breakfast Casserole shows fluffy eggs and melty mozzarella on the Greek yogurt crust. Pin it
A hearty slice of High-Protein Breakfast Casserole shows fluffy eggs and melty mozzarella on the Greek yogurt crust. | olivebriar.com

This High-Protein Pizza Breakfast Casserole is a game-changer for anyone looking to enjoy classic flavors while meeting their protein goals. At 260 calories per serving, it is a balanced and delicious way to fuel your morning routine.

Product image
Keeps spoons and utensils off counters while cooking, catching drips and keeping your stovetop clean.
Check price on Amazon

Frequently Asked Questions

Can I make this ahead of time?

Yes, assemble the entire casserole the night before and refrigerate. Bake in the morning, adding a few extra minutes since it will be cold. Leftovers also reheat beautifully in the microwave.

What can I substitute for Greek yogurt?

Sour cream works as a direct substitute for the Greek yogurt in the dough. For a dairy-free option, try a plain coconut or almond yogurt, though the texture may vary slightly.

Can I freeze this casserole?

Absolutely. Bake completely, cool, then wrap tightly in foil and freeze for up to 2 months. Thaw overnight in the refrigerator and reheat at 350°F until warmed through.

How do I make this vegetarian?

Simply omit the turkey pepperoni or replace it with vegetarian pepperoni slices. You can also add more vegetables like bell peppers, mushrooms, spinach, or diced tomatoes for extra flavor and nutrition.

Can I use different cheeses?

Feel free to experiment with shredded provolone, Monterey Jack, or a Italian cheese blend. Just keep the total amount the same for the best texture and melting results.

20-Minute Dinner Pack — Free Download 📥

10 recipes, 1 shopping list. Everything you need for a week of easy dinners.

Instant access. No signup hassle.

High-Protein Pizza Breakfast Casserole

A protein-packed morning dish with yogurt crust, eggs, pepperoni and cheese.

Prep Time
20 Minutes
Cook Time
25 Minutes
Total Time
45 Minutes


Difficulty: Easy

Cuisine: American

Yield: 6 servings

Dietary: None specified

Ingredients

Greek Yogurt Dough

01 1½ cups all-purpose flour
02 2 teaspoons baking powder
03 ½ teaspoon salt
04 1 cup plain Greek yogurt (nonfat or 2%)

Toppings

01 8 large eggs
02 ½ cup low-fat milk
03 1 cup shredded part-skim mozzarella cheese
04 ½ cup shredded reduced-fat cheddar cheese
05 ½ cup turkey pepperoni slices
06 ½ teaspoon dried oregano
07 ½ teaspoon garlic powder
08 ¼ teaspoon black pepper
09 2 tablespoons chopped fresh parsley

Instructions

Step 01

Prepare the Pan and Preheat Oven: Preheat oven to 375°F. Lightly grease a 9x13-inch sheet pan or casserole dish with cooking spray or butter.

Step 02

Combine Dry Ingredients: In a medium bowl, whisk together flour, baking powder, and salt until evenly distributed.

Step 03

Form Dough Base: Add Greek yogurt to the dry ingredients and mix with a spoon until a shaggy dough forms. Knead briefly until smooth.

Step 04

Press Dough into Pan: Press the dough evenly into the prepared pan, creating a thin, uniform base covering the entire surface.

Step 05

Prepare Egg Mixture: In a large bowl, whisk together eggs, low-fat milk, oregano, garlic powder, and black pepper until thoroughly combined.

Step 06

Assemble Casserole: Pour the egg mixture evenly over the dough base. Sprinkle mozzarella and cheddar cheese over the eggs, then distribute turkey pepperoni slices across the top.

Step 07

Bake Until Set: Bake for 20-25 minutes, or until eggs are fully set and cheese is golden and bubbly.

Step 08

Cool and Garnish: Allow casserole to cool for 5 minutes. Garnish with fresh parsley if desired. Slice into portions and serve warm.

You Just Made Something Great 👏

Want more like this? Get my best easy recipes — free, straight to your inbox.

Join 10,000+ home cooks. No spam.

Tools You'll Need

  • 9x13-inch sheet pan or casserole dish
  • Mixing bowls
  • Whisk
  • Measuring cups and spoons
  • Knife and cutting board

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains wheat (gluten)
  • Contains eggs
  • Contains milk (dairy)
  • Check turkey pepperoni and cheese labels for potential cross-contamination allergens

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 260
  • Total Fat: 10 g
  • Total Carbohydrate: 19 g
  • Protein: 22 g

Cooking Shouldn't Be Hard ❤️

Get a free recipe pack that makes weeknight dinners effortless. Real food, real fast.

Free forever. Unsubscribe anytime.